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—As we expected, our remarks on the articles furnished by Drs. Hutchinson and Cronin, have elicited a letter from each in reply, which we cheerfully insert in this number of the Journal. The first serve only to show what we had suspected, namely, that he had formed his estimate of the teaching in all medical colleges by that of the one he attended in the days when Druitt's Surgery was the most recent text-book. Regarding Dr. Cronin's letter we will only ask, if alcohol undergoes either assimilation or combustion in the human system, how does it happen that during its presence, not only the products of combustion, but the sum total of all eliminations, are diminished, and the temperature reduced, if changed in any direction? If the amount which it is claimed disappears in the system and not capable of being directly recovered in the excretions and eliminations, is actually