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April 4, 1885


JAMA. 1885;IV(14):379-380. doi:10.1001/jama.1885.02390890015006

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Such is the title of an article in the February, 1855, number of the Archives Générales de Médecine, by Albert Robin; an article valuable in that it shows that the administration of carbolic acid in certain infectious diseases, particularly typhoid fever, is worse than useless; and also showing the value of a knowledge of chemistry as applied to therapeutics.

If we analyze a large number of cases of typhoid fever treated by carbolic acid, it is found, says Robin, that the antithermic effect is the only one which really justifies its use. Even then the depression of temperature is only temporary, and to to maintain this it is necessary to prolong the action of the drug for a long time—ten to thirty days. But even the partisans of the carbolic acid treatment report: 1. Nervous symptoms, such as ataxic phenomena, convulsions, chills, trembling, etc.; 2. pulmonary complications; 3. colics, nausea

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