This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Read in the Section of Ophthalmology, Otology and Laryngology of American Medical Association, May, 1884.
Among the many inconveniences from which those directly engaged in the manufacture of chrome suffer, the most prominent, perhaps, consist of a group of symptoms referable to the respiratory tract, and especially the nasal cavities and their dividing septum. In the chrome factory of this city, the workmen employed in the chambers where the bichromate is made, almost invariably acquire perforation of the cartilaginous portion of the latter from the irritating and corrosive action of the fumes and floating dust evolved during the chemistry of its manufacture. This destruction of the cartilaginous septum appears to be the most prominent anatomical lesion, and occurs with such striking frequency, that it may be looked upon as a characteristic and constant sign of this particular form of chrome poisoning. Perforation occurs, as a rule, with great rapidity; generally
MACKENZIE JN. SOME OBSERVATIONS ON THE TOXIC EFFECTS OF CHROME ON THE NOSE, THROAT AND EAR. JAMA. 1884;III(22):601–603. doi:10.1001/jama.1884.02390710013001e
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.