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June 13, 1885


JAMA. 1885;IV(24):669-671. doi:10.1001/jama.1885.02390990025009

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CHOLERA NOTES.  Of great interest just now, especially after the startling array at Munich of Koch's theories, I transcribe some notes from a paper on this subject by Edgar March Crookshank, M.B., of King's College Hospital, London, who has been working up the matter under the very eye of Dr. Babes himself, who, next to Koch, is the best authority in Germany. "The last link in the chain of evidence required to establish the essential rôle of the cholera bacillus in the etiology of cholera is the effect of its inoculation in experimental animals. Nicati, Rietsch, Koch, Ermerigen and Babes have inoculated the bacilli in the duodenum with success. Babes had three satisfactory cases out of six. The operations were performed with all practical antiseptic precautions, and the appearance of the guinea-pig after death showed changes similar to those produced by cholera in the human subject,

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