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Article
June 20, 1885

HÆMORRHAGIC MALARIAL FEVER; PATHOLOGICAL CHANGES IN THE BLOOD AND URINE.

JAMA. 1885;IV(25):686. doi:10.1001/jama.1885.02391000014004

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Abstract

Dr. Jerome Cochrane, of Alabama, in his paper on this subject published in this Journal for May 30th, 1885, has given the results of the analysis of several specimens of the urine from patients laboring under this fever, in which the characteristically dark red urine, which has generally been supposed to contain an abundance of red-blood corpuscles, contained no blood corpuscles whatever. The color was due to the constituents of the blood-corpuscles, chiefly hæmoglobin, without the presence of any nondisintegrated corpuscles in the several specimens of urine examined. The microscopic examinations were made by Dr. Geo. M. Sternberg, U. S. A., and the chemical by Dr. H. Newell Martin, of the Johns Hopkins University. In the same paper Dr. Webb states, in connection with the cases related by him, that in 1875 he sent a specimen of apparently bloody urine from a severe case to Dr. James Tyson, of Philadelphia,

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