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July 30, 1887


JAMA. 1887;IX(5):147-148. doi:10.1001/jama.1887.02400040019003

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Trophic Nerves.  The actual demonstration of the existence of trophic nerve fibres, apart from vaso-motor fibres, has not until recently been made, although many evidences pointing to that conclusion have been put forward. Dr. Joseph, of Berlin, in a number of experiments on cats, produces facts which go to prove the existence of trophic nerve fibres in the peripheral nerves. The complication of vascular changes induced by the removal of the vaso-motor fibres from a part must be excluded in order to prove definitely that any nutritive changes occurring after section of its nerve are due to the loss of trophic influence. These conditions were carefully considered, and in order to avoid any vaso-motor changes, the second cervical nerve was selected for section, which, as will be seen, contains no vaso-motor fibres. This nerve was used in all the experiments. Mere section of the trunk of the nerve produced no

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