Physiologically considered, the uterus is more subject to variations in size than any other organ of the human body. "Its weight, but little more than one ounce in the virgin state, increases during pregnancy to upwards of two pounds. After labor, in two days it falls to a pound and a half; during the first week to one pound. The ceil elements are consumed, compression of nutrient blood-vessels cuts off fresh supplies from the oxidized protoplasm, and in from six to eight weeks the uterus is reduced to almost its normal proportions." If this tearing down and carrying away, by nature's forces, that structure which enveloped the child and nourished it during the period of intra-uterine existence, stops short of completion, we have the condition known as subinvolution or arrested retrograde evolution.
Pathological Anatomy.—Edis says: "In the early stages of subinvolution following parturition, hypertrophy of the muscular structure equally with
EASTMAN J. UTERINE SUBINVOLUTION AND AREOLAR HYPERPLASIA. Read in the Section on Obstetrics and Diseases of Women, at the Thirty-Eighth Annual Meeting of the American Medical Association, June, 1887. JAMA. 1887;IX(12):357–361. doi:10.1001/jama.1887.02400110005001a
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