The Action of Certain Drugs on the Circulation and Secretion of the Kidney.
—In the Section on Therapeutics of the IXth International Medical Congress, Dr. Charles D. F. Philips, of London, read a paper on this subject. It contained a number of very interesting experiments, made with Roy'sonkometer, with caffein, spartein, strophanthin, digitalin and ulexin.1 He concluded that the flow of urine is not so much dependent on the blood-pressure as on the rate of flow of the blood in the renal vessels. With regard to this point, it is necessary to remember that, although such drugs as strophanthin produce a great increase in the force of the cardiac beats, yet these are very much slowed, so that it is quite possible that although the heart's action is stronger, yet the total amount of blood sent through any given organ, such as the kidney, in a given time,
MEDICAL PROGRESS.. JAMA. 1887;IX(15):463–466. doi:10.1001/jama.1887.02400140015002