Malignant disease of the kidneys, regarded from a clinical point of view, occurs either as a primary or secondary lesion. Clinically the latter is of little importance, and the present study will be confined to the primary form. For various reasons the subject is of more than common interest:
—This lesion is quite rare, and our knowledge of it dates back only to very recent times. When Valleix1 published his work in 1853, so few cases of renal cancer had been observed that he remarked: " One may say that no authentic case has occurred where malignant disease was limited exclusively to the kidney. Roberts2 has been able to contribute only four cases as the result of his personal observations. During twenty-two years there were only fifteen cases of malignant renal disease in Guy's Hospital, London. All writers agree as to its infrequency.
—The great diversity of
OUCHTERLONY JA. CLINICAL ASPECTS OF RENAL CANCER, WITH REPORT OF TWO CASES. JAMA. 1886;VII(11):281–286. doi:10.1001/jama.1886.04250090029001
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