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—Poggi, says the American Journal of Psychology, examined the cerebral convolutions of fifty brains of the insane, and found anomalies more common than in the sane, especially in the left hemisphere. The most frequent anomaly is a double calcarial fissure, or communication between the internal occipito-parietal fissure and the sulci of the cuneiform lobule—40 per cent. The brains of the insane are particularly characterized by numerous anastomotic folds.
The Brains of the Insane. JAMA. 1887;IX(20):627. doi:10.1001/jama.1887.02400190019008
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