During the last few years, many instances have been chronicled in both the medical and secular press, suggesting an important connection between the unusual prevalence of typhoid fever and very low water in the streams, wells or other sources of water supply. During the latter part of the past summer and autumn, in many parts of the Mississippi Valley, an extraordinary drouth has prevailed, not only drying up the smaller streams and wells, but reducing the water in the larger rivers to an extraordinarily low level; and coincidently come reports from many localities of the unusual prevalence of fevers, especially of a typhoid type, and in some of dysentery also. During the last few weeks, in Cincinnati, where the Ohio River has been lower than at any time for six or seven years past, the typhoid fever has become so decidedly epidemic as to attract the attention of all classes,