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December 17, 1887


JAMA. 1887;IX(25):797-798. doi:10.1001/jama.1887.02400240029007

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Antipyrin in Sea-sickness—Action of Cocaine on the Digestive Tract—Diet in Gout—Potatoes as Food —Sulphobenzoate of Soda in Wound Dressing.

Since the introduction of antipyrin into the therapeutics of this country by Professor Germain Sée, it has been freely applied to a variety of cases, particularly those in which pain was the predominating symptom. In this it has almost completely supplanted cocaine, at least as an internal remedy. For sea-sickness it is now said to be unrivaled. At a recent meeting of the Société de Biologie, Dr. Dupuly stated that he had tried antipyrin in 11 cases of sea-sickness, and with complete success. He administered it in doses of from 2 to 3 grams daily for two or three days before embarking, and this medication was to be continued during three days after departure. Several theories were then enunciated as to the etiology of sea-sickness, various

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