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March 26, 1887


JAMA. 1887;VIII(13):345-346. doi:10.1001/jama.1887.02391380009003

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Indications for the use of Nitro-Glycerine.  Dr. Trussewitsch, in an instructive paper on the use of nitro-glycerine published in the St. Peters-burger Medicinische Wochenschrift, points out that the value of this drug in various affections—angina pectoris, migraine, and neuralgia (which he describes as angioneuroses), as also in sea-sickness, some forms of anæmia, faintness, palpitation, and other diseases—depends upon the existence of an irregular distribution of blood, which condition may be inferred from a certain degree of pallor of the skin, especially of the face, often co-existent with a weak pulse and a small rigid radial artery, which frequently is situated at some depth. When, on the other hand, headache and neuralgia occur in patients with chronic congestion of the subcutaneous veins of the face, nitro-glycerine is to be avoided; and similarly it is of no use in asthma, when the face is reddened in consequence of emphysema. If, however,

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