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A leading article in the Medical News of the 24th of December, 1887, in referring to "an outline of the modes of treatment in typhoid fever pursued at twelve of the chief hospitals of this country," says: "The use of alcohol is recommended by all the writers, and we have, as yet, no substitute for it in the progressive asthenia of the disease." Before knowing how much value can be awarded to this apparently united testimony in favor of alcohol in typhoid fever, it would be necessary to know how many cases of the fever any one or all of the writers alluded to, have actually treated without alcohol, that they might have a fair basis of comparison of the results. We have tried the experiment of treating typhoid fever and all other general fevers without using alcoholic remedies, both in hospital and private practice for thirty years, and have