Although psoriasis is one of the most clearly defined and well recognized of all diseases of the skin, and has been the subject of much study, clinically and microscopically, we are still in the dark as to its true nature and etiology; moreover, good observers are by no means all agreed as to whether it is a local disease of the skin or one of internal origin. Certain it is that no definite cause has yet been established.
The appearance and character of the individual lesions have time and again suggested a parasitic origin, but as yet no micro-organism has been demonstrated by which the eruption can be produced artificially; nor, on the other hand, has any one constitutional state been shown to be always productive of the eruption. Certain observers have, therefore, characterized it as a local affection of the skin itself, a misbehavior of its cellular elements, even
BULKLEY LD. THE VALUE OF AN ABSOLUTELY VEGETARIAN DIET IN PSORIASIS.. JAMA. 1908;L(8):582–585. doi:10.1001/jama.1908.25310340010001b
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