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Article
March 7, 1908

SARCOMA OF MEDIASTINUM INVADING THYROID.

JAMA. 1908;L(10):766-767. doi:10.1001/jama.1908.25310360028002b
Abstract

This is such an unusual case from the pathologic and clinical standpoint that it seems well worth while to report it:

C. E., male, aged 37, seen Aug. 1, 1907.

History.  —Family history was negative, except that the mother had a goiter at the age of 45. Patient stated he had had only the diseases incident to childhood. The present illness dates from April 1, 1907, when he was working in a shop where there was considerable gas and smoke. He developed an irritating cough, but did not expectorate. He also noticed a difference in his breathing, necessitating a little effort to keep his lungs filled. By the middle of May the cough and breathing had become worse. A month later the cough was quite troublesome; he was slightly hoarse and expectorated some mucus. July 15 he quit work and went north, hoping to get rid of the cough.At

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