Not long since R. A. Hatcher1 made a physiologic examination of a number of preparations of Cactus grandiflorus which certain enterprising pharmaceutic manufacturing companies were exploiting as possessing invaluable therapeutic properties. He evidently went thoroughly into the somewhat limited literature on the subject, and one only needs to refer to his article to find out the present status of our knowledge of the chemistry and the physiologic action of the yet unknown principles contained in Cactus grandiflorus.
As stated by Hatcher, various principles derived from the different members of the cactus family have been subjected to physiologic examination, but few and incomplete are the researches on the physiologic action of anything found in Cactus grandiflorus. This is probably due to the fact that no one has been able, thus far, to isolate any substance which could be said, with any degree of certainty, to be either an alkaloid or
MATTHEWS SA. "CACTIN" AND "CACTINA;" AN EXAMINATION INTO THEIR PHYSIOLOGIC ACTION. JAMA. 1908;L(12):956–958. doi:10.1001/jama.1908.25310380028002e
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