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Article
April 4, 1908

SUBACUTE COMBINED CORD DEGENERATION, WITH REPORT OF CASES.

JAMA. 1908;L(14):1109-1115. doi:10.1001/jama.1908.25310400021002d
Abstract

Although writers have previously reported cases that appear to belong to this disease, our first definite knowledge of it began in 1887, when Lichtheim1 reported three cases of pernicious anemia with symptoms indicating spinal cord involvement. His pupil, Minnich,2 followed with a series of cases, in some of which he was able to demonstrate the cord changes in the posterior and lateral tracts. Then came the excellent reports of Von Noorden,3 Eisenlohr,4 Nonne,5 Bowman,6 James Taylor,7 Burr,8 Michell Clark,9 Risien Russell10 and others, who described a similar pathology in the cords of those dead from pernicious anemia, secondary anemia and from exhausting disease without anemia. To Putnam11 of Boston belongs the credit of having been the first to point out that the cord lesions which had been often described in connection with pernicious anemia are in no wise characteristic

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