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May 23, 1908


JAMA. 1908;L(21):1688. doi:10.1001/jama.1908.25310470026002b

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I wish to report a case of tetanus treated with magnesium sulphate by hypodermoclysis, with recovery:

The patient, J. K., male, 7 years old, stepped on a nail, which punctured the sole of his shoe and entered the left foot, barely through the skin, making a wound scarcely noticeable.

Eight days later he complained of stiffness in his foot and leg. On the ninth day a spasm of the leg caused him to fall, and rigidity of muscles was increased. On the tenth day trismus was noticed and there were occasional convulsions. On the eleventh day I was called to see him and found his jaws set and almost all his muscles rigid. He could move his arms and hands to a limited extent. The wound was laid open and thoroughly treated with hydrogen dioxid and tincture of iodin.

The convulsions were partially controlled by morphin, chloral and bromids. On

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