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Article
June 13, 1908

THE PHLORIDZIN TEST.WITH SPECIAL REFERENCE TO THE INFLUENCE EXERTED BY A DISEASED KIDNEY ON THE EXCRETORY WORK OF THE SECOND ORGAN.

JAMA. 1908;L(24):1972-1975. doi:10.1001/jama.1908.25310500020002b
Abstract

I shall limit myself to the report of seven selected cases,1 which I believe demonstrate that a diseased kidney may so affect the excretory activity of the second kidney as to mislead all who rely too much on our present functional tests. I shall not deal with those disturbances of the second kidney that we see in acute obstructive conditions of the diseased side and which have been produced experimentally by Götzl. These lead to oliguria or to complete, though usually only temporary, anuria, and are best explained on a nervous basis as instances of reflex inhibition. I shall confine myself to the more chronic conditions in which excretory functional tests are possible. Moreover, I shall not discuss the degenerative changes in the second kidney, so-called sympathetic or toxic nephritis induced by disease of the impaired kidney. These changes evidenced by albumin and casts in the secretion of the

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