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August 1, 1908


JAMA. 1908;LI(5):393-396. doi:10.1001/jama.1908.25410050033002i

It almost requires an explanation for presenting any phase of a subject that has been considered so extensively in recent years as pernicious anemia, but the phenomena of remissions form a sufficiently interesting chapter in the disease to warrant its being made the theme of this brief paper.

A remission signifies but an abatement of symptoms, and so rarelydoes a complete restitution take place that it is to be regarded as a temporary period of improvement and not a cure. The earlier writers who coined the term progressive pernicious anemia evidently did not give due cognizance to the phenomena of remissions, because a disease process that is subject to remissions of improvement, or periods of latency, can hardly be regarded as distinctly pernicious; the term progressive is applicable in that it is not possible to bring the process to a standstill or promote a cure.

Out of a series of

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