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Article
September 5, 1908

HYPERSUSCEPTIBILITY TO HORSE SERUM.

JAMA. 1908;LI(10):840-841. doi:10.1001/jama.1908.25410100040002a

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Abstract

As a contribution to the reports of cases of reactions following the injection of antitoxic sera, I wish to add the following report. It is, I believe, the first case reported in which this reaction has followed the injection of tetanus antitoxin.

Patient.  —A young man of 24 years, on June 16, 1908, sustained a punctured wound of his left foot by stepping on a rusty nail at an iron-yard. He went to the Jewish Hospital, where he was placed on the service of Dr. Joseph Ransohoff. Under local cocain anesthesia a triangular-shaped area of skin and subcutaneous tissue about one-half inch deep, and containing the wound, was excised from the plantar surface of the foot, and the resulting wound thoroughly cleansed. Throughout the operation the patient was perfectly composed and was not distressed in any way.

Administration of Serum.  —A prophylactic injection of 10 c.c. (1,500 units) of tetanus

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