Adenomata of the islands of Langerhans have seldom been described in the literature, probably because they are accidental findings in the routine examination of autopsy material rather than because they are actually very rare. Nichols,1 in 1902, reported one which he believed was the first of the kind on record, and Helmholtz,2 in 1907, added a second case. The reader is referred to their articles for a discussion of several other tumors described as arising from the islands of Langerhans, but apparently of doubtful origin. A search through the literature reveals no additional cases. Recently, however, two tumors of this kind have come under my observation. The first was found at the New England Hospital in the service of Dr. Clara J. Alexander; the second at the Boston City Hospital by Dr. O. R. Mabee, through whose courtesy I am enabled to report it. Both were discovered at
MORSE ME. TWO ADENOMATA OF THE ISLANDS OF LANGERHANS. JAMA. 1908;LI(13):1075–1076. doi:10.1001/jama.1908.25410130031003c
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