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December 26, 1908


JAMA. 1908;LI(26):2215-2216. doi:10.1001/jama.1908.25410260017001e

Newborn babies are specially prone to develop hemorrhages, and because of the indefinite knowledge to-day of the true pathology of the condition, the symptom-complex is now called in general terms, "hemorrhages of the newborn." Formerly an attempt was made to describe each case according to the location of the hemorrhage, in this way having a number of terms descriptive of the same general underlying disease. King, Genrich and Runge, quoted by Koplik, state that hemorrhagic disease in the newborn occurs about once in a thousand cases. Shukowsky's estimate of twenty-nine in thirty thousand agrees with this statement.

ETIOLOGY.  The etiology of the condition is obscure; but in view of the fact that fever is a prominent symptom in most cases, the general consensus is that the most frequent causative factor is a general septic infection. The newborn develop sepsis easily and the entrance of the offending organisms to the system