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Article
January 2, 1909

THE ORIGIN OF THE BEAT OF THE HEART AND ITS CONDUCTION THROUGH THE HEART

JAMA. 1909;LII(1):53. doi:10.1001/jama.1909.02540270061005
Abstract

It seems possible that the two hypotheses known respectively as the myogenic and the neurogenic theory of the rhythmicity of the heart beat may at last coexist on friendly terms. Recent work tends in this direction, as it seems to grant to the neurogenists the control of the heart, and possibly also the origin of the impulse which results in a beat, and to the myogenists the path of conduction of this impulse.

Based originally on the assumption that the conduction of an impulse passing from the atrium to the ventricle accounts for the difference in time between the atrial and ventricular systoles, the myogenic theory was substantiated in 1893 by the younger His.1 His researches and Retzger's2 more complete work later demonstrated the path of conduction of this impulse — a muscle bundle connecting the atrium and ventricle through the atrio-ventricular septum. The production of independent atrial

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