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March 6, 1909


JAMA. 1909;LII(10):776-777. doi:10.1001/jama.1909.02540360032007

The recent activity in the field of teratology is more than a revival of the older descriptive methods. Parallel with Mall's1 studies on the causes underlying the origin of human monsters, we have had an extensive series of researches in the field of experimental teratology, of which the latest and most striking examples are seen in the artificial production of cyclopean monsters by Stockard and Lewis. Stockard2 finds that by treating the eggs of the common minnow, Fundulus, with solutions of magnesium chlorid immediately after fertilization he can produce at will as high as 50 per cent, of cyclopean monsters of various degrees of abnormality. Dr. Warren H. Lewis3 has reported a parallel series of experiments in which he has produced almost identical defects in the same species of fish by destroying in later developmental stages the extreme anterior end of the medullary plate before it has