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Article
March 6, 1909

THE LONGEVITY OF LEUCOCYTES IN ALIEN SERUM

JAMA. 1909;LII(10):778. doi:10.1001/jama.1909.02540360034009
Abstract

We are just beginning to realize the possible applications of experimental serologic and biologic methods to diagnosis. Since the clinical application of Pfeiffer's phenomenon other serobiologic tests have been devised, notably Uhlenhuth's test for blood stains, Wassermann's test for syphilis, and Wright's test for opsonins. Recently, we believe, there have been suggestions that the phenomena of anaphylaxis may be utilized in the diagnosis of tuberculosis. An interesting line of investigation, as yet but partly worked out, has been suggested by H. C. Ross. He has devised a method of estimating the life of leucocytes after they are removed from the body, and has tested the effect of the plasma of other persons, healthy or suffering from infectious diseases, on the leucocytes of normal individuals. He finds that normal leucocytes in their proper plasma live a considerable length of time, over forty-eight hours very often, outside the body. He also shows

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