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March 27, 1909

INTERTRANSMISSIBILITY OF BOVINE AND HUMAN TUBERCLE BACILLIEVIDENCE OFFERED BY CLINICAL ADMINISTRATION OF TUBERCULINS MADE FROM BACILLI OF HUMAN AND BOVINE ORIGIN

JAMA. 1909;LII(13):1007-1011. doi:10.1001/jama.1909.25420390003001a

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Abstract

The question of the intertransmissibility of tubercle bacilli of the human and bovine varieties is a purely scientific one and can be settled only by carefully weighing scientific data. It was on this ground that Koch objected to resolutions being passed on this subject at the International Tuberculosis Congress, taking the stand that it was impossible to settle or add anything to a scientific question by passing resolutions.

DIFFERENT VARIETIES OF BACILLI PROBABLY ORIGINALLY FROM ONE SOURCE  If we approach this study with the knowledge which we have derived from observations in other fields, it is not difficult for us to believe that the different varieties of tubercle bacilli originally came from one single source, but that through adaptation, the one to man, another to animals, and a third to birds, they have finally so changed that they now differ in form, method of growth, virulence toward animals and other

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