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April 10, 1909


JAMA. 1909;LII(15):1184-1185. doi:10.1001/jama.1909.02540410032005

It is a long-recognized fact that the sodium chlorid solutions ordinarily used in experimental study of problems in immunity afford only an approximation to the conditions actually present in the living organism. In view of this fact, Pick and Schwarz1 recently carried out some experiments under conditions different from the ordinary, which not only give interesting results, but are of great value in furnishing suggestions for future work. The fluids of the body, in addition to their content of inorganic salts, also contain to a considerable extent so-called lipoids, that is, substances having the general property of being soluble in the organic fat solvents. It was the rôle of these lipoids in immune processes that was investigated; the lipoids used were lecithin and alcoholic extracts of various organs and of blood constituents.

It was found that the use of a lecithin emulsion in place of sodium chlorid emulsion in