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May 22, 1909


JAMA. 1909;LII(21):1669. doi:10.1001/jama.1909.02540470035005

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We are approaching the end of the solution of a problem which for many years has been the subject of bitter controversy and during the past eighteen years has been the object of perhaps more extensive work than any other in medicine. The relation of human and bovine tuberculosis is a question of first importance and deserving the most careful consideration.

The investigations which have led up to the proof of he intercommunicability of the disease in man and cattle may be divided into three periods: first, those taking place before the publication, in 1882, of the discovery of the tubercle bacillus by Koch; second, those occurring between the time of the discovery of the tubercle bacillus and its differentiation into human and bovine types by Theobald Smith in 1896-1898; third, those occurring since the establishment of these two types.

During the first period, it was shown by direct experiment

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