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Epulis is a slightly malignant tumor of the jaw, growing from the connective-tissue cells between the mucous membrane and the periosteum of the alveolar border.The tumors grow slowly, seldom reach a large size, or cause destruction of the bone. The teeth are often loosened by the growth of the tumor into the root sockets. As far as is known, these tumors never give metastases, but will recur locally if their removal is not complete. Histologically they are sarcomata of low malignancy, gaint-celled and fibro-spindle-celled, or vascular fibromata (angiofibroma). An epulis always may be cured by complete excision.These tumors seem closely related to inflammatory reaction. About 25 per cent. of cases give a distinct history of traumatism as an etiologic factor. A certain number of patients date the growth of the tumor from the extraction
McGLANNAN A. GIANT-CELL EPULIS OF LOWER JAWREPORT OF A CASE. JAMA. 1909;LIII(5):379–381. doi:10.1001/jama.1909.92550050041003a