It is but a half-dozen years since Hofmeister aroused some attention by adding up the number of different enzymes which each liver cell must contain to accomplish the various chemical functions known to occur in these cells, the total number being something like ten. The worthy German scholar, however, missed some enzymes, for which there was good evidence even at that time, and if he were to rewrite his address now he would show that newer investigations have brought to light several more enzymes that should go on the list. Even with the respectable total of this revised catalogue of hepatic activities before us, we still must feel that as yet we have secured but a most superficial glance at the obvious industries of that busy little workshop, the liver cell, for new investigations into the metabolic activities of the liver continue to unfold new functions hitherto unsuspected, or at
THE RELATION OF THE LIVER TO FAT METABOLISM. JAMA. 1909;LIII(15):1190–1191. doi:10.1001/jama.1909.02550150046004
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