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October 9, 1909


JAMA. 1909;LIII(15):1192. doi:10.1001/jama.1909.02550150048006

Blastomycetic infection of the skin is now, thanks largely to the investigations of American observers, a well-recognized morbid condition. A considerable amount of literature has recently accumulated dealing with infections, not only of the skin, but of other tissues, by a fungus related to the Blastomycetes, the so-called Sporotrichum.

Schenck,1 in 1898, observed a case of multiple, small, very refractory ulcerations of the skin of the right forearm which had formed along the course of the lymphatics leading from an ulcer of the index finger. The ulcers had resulted from the breaking down of small, circumscribed subcutaneous indurations. Cultures were made from the ulcers and indurated nodules, and Schenck's subsequent studies showed that the causative organism was a Sporotrichum, a fungus of the order Hyphomycetes, which grows readily on all the usual culture media. Schenck was able to reproduce the skin lesions in a dog by subcutaneous injections of