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A new edition of a book frequently means simply a new impression with no alterations whatever. With the work before us, however, it is different. We quote from the preface: "Particular attention has been given to therapeutic details in accordance with the recent awakening of the profession to the importance of logical treatment; numerous new preparations and modified names and dosages, particularly for children, are explicitly specified. There are practically new chapters on the arrhythmias and other cardiac neuroses, tropical splenomegaly and various other tropical affections. Due consideration has been given to the meningitis serum of Flexner and Jobling, Strong's work on amebic dysentery, blood cultures in typhoid and other bacteriemias, the "carriers of infection," the recent epidemics of meningitis and poliomyelitis, the accumulating evidence in favor of the spirochete as the cause of syphilis, and the recent status of tuberculin in its therapeutic application and in its various diagnostic
A Treatise on the Principles and Practice of Medicine. JAMA. 1909;LIII(17):1428. doi:10.1001/jama.1909.02550170084028
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