In a recent comment2 on the transmission of acute poliomyelitis to monkeys, by Landsteiner and Popper, we stated that, while further experiments were necessary, it seemed that a method had been found by the help of which our knowledge of the cause of poliomyelitis would be advanced. The report by Flexner and Lewis in this issue of The Journal, showing their success in transmitting acute poliomyelitis to monkeys and of maintaining the disease in those animals, is of great interest in this connection. Landsteiner and Popper failed in their efforts to communicate the disease from monkey to monkey, possibly because of the method employed. Flexner and Lewis, using the intracranial method of inoculation, have established that it is possible to carry the virus of epidemic poliomyelitis successfully through a series of monkeys, and it seems likely that the disease may be maintained in this animal indefinitely. This advances greatly
THE TRANSMISSION OF ACUTE POLIOMYELITIS TO MONKEYS. JAMA. 1909;LIII(20):1646. doi:10.1001/jama.1909.02550200040009
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