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December 11, 1909


JAMA. 1909;LIII(24):2002-2003. doi:10.1001/jama.1909.92550240048002a

Acute uremias, dependent on intoxication from any cause, are of such uncertainty of occurrence and so serious in results that the report of a specific case with its treatment and recovery is not without justification. The case in question was sequel to a typically severe infection of scarlet fever which terminated on the sixteenth day by fall of temperature without complication, with no deficiency in urinary secretion or appearance of albumin.

The initial signs of the attack were first observed four days after the fall of temperature, with the child, a previously healthy boy of 7 years, in bed and on a liquid diet. In the evening of the fourth da}', following a cup of broth, the patient was nauseated, but without emesis, and soon fell asleep. In the early morning following, when he had been thought to be sleeping, he was observed to be twitching about the muscles of

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