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February 12, 1910

EPIDEMIC POLIOMYELITIS IN MONKEYSA MODE OF SPONTANEOUS INFECTION

JAMA. 1910;LIV(7):535. doi:10.1001/jama.1910.92550330001001l
Abstract

In our previous communications1 on experimental poliomyelitis, we have left entirely undiscussed the manner in which the virus of epidemic poliomyelitis enters and leaves the human body, points which we propose to discuss in the present note. Our studies having supplied the basic fact of the nature of the virus,2 it became possible to attack the question of the mode of transmission of the spontaneous disease. That epidemic poliomyelitis is an infectious disease has long been suspected, but that it is also a highly contagious one is far less generally admitted. And yet the studies on its epidemiology by Wickman3 lend considerable support to the latter view.

In the first place, we wish to draw attention to the frequently observed fact that in point of distribution epidemic poliomyelitis resembles epidemic cerebrospinal meningitis. The two diseases, indeed, present, in this respect, such close similarities that they have often been confounded with

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