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Mrs. N., aged 58, suffering from varicose ulcer, lower third, right leg, was under the care of her family physician for some time. Among the various drugs used was vioform. A few hours after applying this preparation a dermatitis developed which soon became generalized, with all of its concomitant symptoms and in addition both limbs showed below the knees an extensive purpura. This condition cleared up very quickly under withdrawal of drug and proper treatment.
I report this because I think that it is the first case of dermatitis following the use of this drug to be published.
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POTTHOFF EW. DERMATITIS FOLLOWING VIOFORM. JAMA. 1910;LIV(10):792. doi:10.1001/jama.1910.92550360001001i
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