[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
March 12, 1910


Author Affiliations


JAMA. 1910;LIV(11):859-866. doi:10.1001/jama.1910.92550370001001f

Who shall decide, when doctors disagree, And soundest casuists doubt, like you and me? Pope, Epistle to Lord Bathurst.

Since the inception of the discussion relative to the disease pellagra, which now occupies the attention and interest of the profession and the country at large, especially the South, much has been said and written concerning the malady. While on the whole the contributions contain much that is valuable, yet into the published reports of these investigations have crept many errors and divergencies, notably with respect to the etiology. The interest in the disease is apparently so extensive that I believe that I am justified in offering the subjoined review of the findings and theories of those members of the profession whose labors on the subject have justly caused them to be regarded as foremost authorities.

The expressions of the early clinicians who in dealing with this disease likened it