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To the Editor:
—The period of so-called "rose cold" or "vernal hay fever"—i. e., vernal, pollenogenic, angioneurotic edema of the air passages—is approaching, or with certain patients, here. Referring to my observations in 1898 concerning the use of adrenal preparations in this disorder and in asthma (since confirmed throughout the world) I wish now to ask physicians to use preparations of the pituitary gland, and more especially of the infundibulum or posterior lobe. There are at least two, and possibly several, good commercial preparations now available.From the recoveries which I have observed to follow their use in Quincke's edema, asthma, recurrent erythema and other angioneuroses, as well as their effects in "opening" the nasal passages, I should expect them to be superior to the adrenal preparations in all varieties of hay fever. The action is slower, but more persistent.The pituitary extracts may be used both topically and systemically.
Cohen SS. Pituitary Extracts in Hay Fever, Asthma, Etc. JAMA. 1910;LIV(22):1803. doi:10.1001/jama.1910.02550480047013
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