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The remarkable progress which has been made during the past twenty years in the surgical treatment of Graves' disease is worthy of comment. This progress is due to a greatly increased knowledge of the disease, and has resulted in a reduction of the mortality, in a greater number of cures, or in greatly lessened disability.
In the early nineties the disease was considered from a purely medical point of view, and very often patients were nearly moribund before surgical aid was given. It has been shown, however, that the disease is chronic and that there are conditions and periods of activity peculiar to it which should he treated medically in preparation for an operation later, unless the improvement be continuous and the recovery complete.
Because of the severe symptoms which present themselves the majority of cases of exophthalmic goiter can be readily diagnosed as such, but there may be
MAYO CH. FACTORS OF SAFETY IN OPERATING FOR EXOPHTHALMIC GOITER. JAMA. 1912;LIX(1):26–27. doi:10.1001/jama.1912.04270070028010
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