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The usual type of congenital or early cerebral paralysis is accompanied by a more or less normal growth of the body. The type to be described differs from the foregoing in the fact that there is a lack of development accompanied by an atrophy of all the parts of the body except the bony skeleton, which atrophic condition modifies the symptomatology. While the atrophic type of cerebral palsy, which is of fairly rare occurrence, has been parenthetically noted by various writers, it has not generally been allotted its place in the classification of cerebral palsies.
The special pathology of this atrophic form is dependent on a lower cortical involvement than the ordinary type. The abnormalities involve the pituitary body and the pons, but, strangely, do not markedly affect the cranial nerves. The pathology of Little's disease has never been very satisfactory and remains questionable. In the form which I shall
RICH EA. THE ATROPHIC FORM OF LITTLE'S PARALYSIS. JAMA. 1912;LIX(3):175–177. doi:10.1001/jama.1912.04270070176006
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