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In every important pathologic cycle there is a focal point from which the disease process emanates and radiates. There is no small individual cavity in the human body which occupies so distinctly vital a position in its relations to surrounding areas as does the cavum tympanum. A brief study of its anatomic relations will definitely reveal the close interrelation which exists between the cavum tympanum and its many accessory areas, viz.: the eustachian tube. the mastoid antrum, the lateral sinus, the carotid canal, the labyrinth and the temporosphenoidal fossa.
The irregularly shaped cavity of the middle ear is located in a comparatively inaccessible place in the depth of the temporal bone, surrounded on all sides by delicate and vital structures. It offers a favorable site for fluid contents and an ideal incubator for the many forms of bacteria which so frequently find lodgment there. It is most vulnerable, of course,
GOLDSTEIN MA. DISEASES OF THE EAR WHICH LEAD TO BRAIN ABSCESS. JAMA. 1912;LIX(12):1101–1107. doi:10.1001/jama.1912.04270090345066
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