—In March, 1909, J. E. P., a man aged 48, 6 feet in height, well proportioned and weighing 180 pounds, consulted me because of a general depression and inability to work, either mentally or physically. He had been in failing health for several years. He complained of headache, shortness of breath and at times difficult vision. There had been a progressive loss of weight for live years; previous to the beginning of this illness, it averaged from 200 to 220 pounds. The patient was conscious of an irregular action of the heart, which, he said, had developed within the past six months; it was this irregularity, together with shortness of breath on even moderate exertion, for which he sought relief. There was some irritation of the bladder, especially at night, but no prostatic trouble. His general appearance gave one the impression of a once active, energetic business man
PERCY JF. THYROID EXTRACT IN NEPHRITIS: A PRELIMINARY STATEMENT OF A NEW AND EFFECTIVE METHOD OF TREATMENT. JAMA. 1912;LIX(19):1708–1710. doi:10.1001/jama.1912.04270110122018
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