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December 7, 1912

Immunity in Pneumococcus Infections

JAMA. 1912;LIX(23):2085-2086. doi:10.1001/jama.1912.04270120070026

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To the Editor:  —In The Journal, Oct. 12, 1912, there appeared an article by Dr. J. O. Hirschfelder, of San Francisco, on active and passive pneumococcus immunity. This article is a valuable communication and Dr. Hirschfelder is to be congratulated on the resourcefulness and ingenuity of his experiments and deductions. His work is of unusual interest to me, since it parallels certain observations of my own, which have been in progress since November, 1910. My own work has been concerned chiefly with studies of a group of organisms which has the common characters of autolysis and enzyme production, namely, the pneumococcus, the gonococcus and the meningococcus, and to a lesser degree the staphylococcus. Of these organisms, the pneumococcus alone lends itself to animal experimentation, and the work of Rosenow and others has done much to clear up the nature of the autolytic processes and the chemical and biologic characters of

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