[Skip to Content]
[Skip to Content Landing]
February 16, 1889

Treatment of Pseudo-Membranous Laryngitis or Croup.

JAMA. 1889;XII(7):251. doi:10.1001/jama.1889.02400840035015

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Dear Sir:  —Some time in 1887 my attention was called to the fact that some pepsins (notably the vegetable product styled "papayotin" by Parke, Davis & Co., and "papoid" by Johnson & Johnson), will digest diphtheritic membranes; it will digest those that are true false-membranes and not infiltrations of the mucous membrane. Acting on this hint I have applied the same treatment to membranes within the larynx, by making a solution ([unk]j to f[unk]j water) and using it very frequently as a spray by means of the hand-ball apparatus. Where the child resists, as is common, I sometimes use an oval speculum. Of course this does not supersede other treatment. I have not had an opportunity to use this often enough to generalize, but I have succeeded in saving every case of croup I have treated since commencing to use it; and I verily believe that, where it is used

First Page Preview View Large
First page PDF preview
First page PDF preview