Efforts to frame a satisfactory etiological classification of mental disease have been materially helped by a resort to a clinical grouping of cases. It has been recognized that where a wide variation exists in the causes assigned for the production of insanity in any given series of cases, among certain of them "groups of symptoms" are manifested which point to a definite constantly acting cause. "In many instances we know absolutely that such a cause exists. Even if we do not know that a specific cause is antecedent to the development of a certain form of disease, we are justified in inferring, where symptoms are identical, an identity of cause." Acting upon this theory, it has been possible to frame a rational classification or "clinical grouping" that has simplified much that has hitherto been unsatisfactory and obscure. In spite, however, of the material assistance thus afforded, the lack of a
CHRISTIAN EA. CHRONIC BRIGHT'S DISEASE (ARTERIO-CAPILXARY FIBROSIS) IN ITS RELATIONS TO INSANITY. JAMA. 1889;XII(12):397–403. doi:10.1001/jama.1889.02400890001001
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