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In a communication on the " Sensibility of the Bladder in the Normal and Pathological State," made to the Académie des Sciences, on March 14, Professor Guyon said that in the normal state the sensibility of the bladder is manifested only when the desire to micturate is felt. To determine under what physiological conditions this desire is produced was the object of some researches undertaken by him. These researches have led to the following conclusions: 1. In the physiological state the desire to urinate is felt only under the influence of tension of the vesical walls. 2. Contraction of the vesical muscle precedes immediately the manifestation of this desire, which is perceived only when this contraction is carried to a certain degree. 3. The desire to micturate does not depend upon the action of a sort of elective sensibility, having a special centre in a determined point of the mucous membrane
THE SENSIBILITY OF THE BLADDER. JAMA. 1889;XII(13):451–452. doi:10.1001/jama.1889.02400900019003
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