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It has taken practically over twenty-two years to develop the exact pathology of tuberculosis up to its present degree of completion. Since 1865, when Villemin proclaimed that by vaccination with tuberculous matter, an identical process like that of human tuberculosis could be brought forth in some of the lower animals, the contagious and infectious character of tuberculosis was partly believed or assumed by many, This, however, does not eclipse in the least the brilliancy of Robert Koch's discovery of the specific cause of tuberculosis, nor does it alter the fact that this same discovery is unquestionably the most significant advance made in pathological investigation. Before Koch's memorable communication to the Berlin Physiological Society, the "cheese infection theory," as explained by Buhl, and the weakly "diathesis theory," strove for supremacy as the disguise for real ignorance as to the true cause of the tubercular process.
The student who desires a plain
PIERCE NH. THE BACILLUS OF KOCH, AND ITS PATHOLOGICAL INFLUENCE. Read before the Chicago Medical Society, February 18, 1889. JAMA. 1889;XII(15):510–514. doi:10.1001/jama.1889.02400920006001a
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