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April 27, 1889


JAMA. 1889;XII(17):591-594. doi:10.1001/jama.1889.02400940015003

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Regarding the Resemblance of the Malaria-parasite to those of Febris Recurrens.  —N. A. Sacharoff, in a preliminary communication in Wratsch., 1889, No. 1 (Russian), states that there exists in the blood of patients suffering from febris recurrens a hæmatazoon which may be best observed immediately after the temperature begins to fall, and which then assumes enormous proportions (20 and more diameters of a red blood-corpuscle). But specimens of lesser size are also found. The parasite consists of a delicate amœboid body containing a multitude of dark, round, uniform, sharply-outlined movable granules. Besides these the protoplasma contains a generally grayish, homogeneous nucleus as large as one or two red blood-corpuscles. The protoplasma sends forth pseudopodia (without granules) which sometimes separate from it and appear as small, delicate pieces of protoplasma without granules. They vary in size and are often swallowed by red blood-corpuscles in which they gradually grow and finally develop

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